(-)-Epigallocatechin Gallate
作者：齊岳
發(fā)布時間：2023-09-11
09:06:58
點擊數(shù)：
產(chǎn)品名稱：(-)-Epigallocatechin Gallate
產(chǎn)品描述：
| 植物來源 | 天然產(chǎn)物 > 豆科 > 相思樹屬 |
| 結(jié)構(gòu)類型 | 天然產(chǎn)物 > 酚類 |
| 產(chǎn)品描述 | Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. EGCG is a phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. |
| 體內(nèi)活性 | Epigallocatechol Gallate (5 and 20 mg/kg, p.o.) inhibits the growth of tumor in the subcutaneous orthotopic transplant model[4]. |
| 細胞實驗 | LoVo, SW480, HCT-8, and HT-29 cells are seeded in 96-well plates at a concentration of 5×103?cells; each cell line is totally seeded in the 12 wells. Complete medium is added to the wells, up to 200 μL; the medium contains 0 μg/mL, 10 μg/mL, 20 μg/mL, and 35 μg/mL of epigallocatechol gallate. The inhibition rate=[1 - (absorbance of Epigallocatechol Gallate group - absorbance of control group)/(absorbance of control group - absorbance of blank control group)] × 100. |
| 別名 | EGCG, Epigallocatechol Gallate, (-)-表沒食子兒茶素沒食子酸酯 |
| 分子量 | 458.38 |
| 分子式 | C22H18O11 |
| CAS No. | 989-51-5 |
存儲
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
H2O: 4.6 mg/mL (10 mM)
Ethanol: 45.8 mg/mL (100 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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