α-Vitamin E
作者：齊岳
發(fā)布時間：2023-09-07
09:28:14
點擊數(shù)：
產(chǎn)品名稱：α-Vitamin E
產(chǎn)品描述：
| 結(jié)構(gòu)類型 | 天然產(chǎn)物 > 酚類 |
| 產(chǎn)品描述 | (+)-α-Tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. |
| 體外活性 | vitamin E is capable of inducing necrosis in TC-1 cells and has antioxidant effects against nitric oxide[1]. |
| 體內(nèi)活性 | Vitamin E induces TC-1 cell necrosis in vivo and reduces tumor volume in TC-1 tumor-bearing mice. Vitamin E reduces myeloid derived suppressor cells(MDSCs) in tumors of TC-1 tumor-bearing mice and enhances T cell accumulation[1]. |
| 細(xì)胞實驗 | For in vitro cytotoxicity experiments, 1×105 TC-1 cells per well are added to 24-well plates. Eighteen hours later, tumor cells are treated with Vitamin E (0, 25, 50 μM). After 18 hours, apoptotic (Annexin V+ and 7AAD−) and necrotic (Annexin V+ and 7AAD+) cells are measured using PE Annexin V Apoptosis Detection Kit I. (Only for Reference) |
| 別名 | 天然維生素E, Dexrabeprazole Sodium, 5,7,8-Trimethyltocol, D-α-生育酚, Alpha-Tocopherol, (+)-alpha-Tocopherol, Vitamin E, D-α-Tocopherol |
| 分子量 | 430.71 |
| 分子式 | C29H50O2 |
| CAS No. | 59-02-9 |
存儲
| Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 12 mg/mL (27.86 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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