Mitraphylline
作者：齊岳
發(fā)布時(shí)間：2023-09-06
09:05:29
點(diǎn)擊數(shù)：
產(chǎn)品名稱：Mitraphylline
產(chǎn)品描述：
| 植物來源 | 天然產(chǎn)物 > 茜草科 > 鉤藤屬 |
| 結(jié)構(gòu)類型 | 天然產(chǎn)物 > 生物堿 |
| 產(chǎn)品描述 | Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils. |
| 體外活性 | The alkaloids of Uncaria tomentosa micropropagated plantlets and root cultures were isolated and identified by NMR and mass spectrometry. Plantlets yielded pteropodine (1), isopteropodine (2), Mitraphylline (3), isoMitraphylline (4), uncarine F (5), speciophylline (6), rhynchophylline (7) and isorhynchophylline (8). In plantlets growing under continuous light, tetracyclic alkaloids 7 and 8 decreased from 20 ± 1.8 at 2 months to 2.2 ± 0.33 mg/g dry wt at 6 months, while the pentacyclic alkaloids 1-4 increased from 7.7 ± 1.4 to 15 ± 0.05 mg/g dry wt, supporting their biogenetic conversion. Micropropagated plantlets produced four times more alkaloids (27.6 ± 3.1 mg/g dry wt) than greenhouse plants. |
| 別名 | 帽柱木菲堿, 帽柱葉堿 |
| 分子量 | 368.43 |
| 分子式 | C21H24N2O4 |
| CAS No. | 509-80-8 |
存儲(chǔ)
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
DMSO: 6.76 mg/mL (18.35 mM),Need ultrasonic
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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